Reproductive Epidemiology / en New study finds association between insecticide exposure and lower sperm concentration in adult men /news/2023-11/new-study-finds-association-between-insecticide-exposure-and-lower-sperm-concentration <span>New study finds association between insecticide exposure and lower sperm concentration in adult men </span> <span><span lang="" about="/user/376" typeof="schema:Person" property="schema:name" datatype="" xml:lang="">mthomp7</span></span> <span>Tue, 11/14/2023 - 17:30</span> <div class="layout layout--gmu layout--twocol-section layout--twocol-section--30-70"> <div class="layout__region region-first"> <div data-block-plugin-id="field_block:node:news_release:field_associated_people" class="block block-layout-builder block-field-blocknodenews-releasefield-associated-people"> <h2>In This Story</h2> <div class="field field--name-field-associated-people field--type-entity-reference field--label-visually_hidden"> <div class="field__label visually-hidden">People Mentioned in This Story</div> <div class="field__items"> <div class="field__item"><a href="/profiles/mperry27" hreflang="en">Melissa J. Perry, Sc.D., MHS</a></div> </div> </div> </div> <div data-block-plugin-id="inline_block:call_to_action" data-inline-block-uuid="6882b179-2851-4d2a-a64d-a11e441e1a6b"> <div class="cta"> <a class="cta__link" href="https://publichealth.gmu.edu/media-association-between-insecticide-exposure-and-lower-sperm-concentration"> <h4 class="cta__title">Media Inquiries Learn More <i class="fas fa-arrow-circle-right"></i> </h4> <span class="cta__icon"> <div class="field field--name-field-cta-icon field--type-entity-reference field--label-visually_hidden"> <div class="field__label visually-hidden">Icon</div> <div class="field__item"><div> <div class="field field--name-field-media-font-awesome-icon field--type-fontawesome-icon field--label-visually_hidden"> <div class="field__label visually-hidden">Icon</div> <div class="field__item"><div class="fontawesome-icons"> <div class="fontawesome-icon"> <i class="fas fa-newspaper" data-fa-transform="" data-fa-mask="" style=""></i> </div> </div> </div> </div> </div> </div> </div> </span> </a> </div> </div> </div> <div class="layout__region region-second"> <div data-block-plugin-id="field_block:node:news_release:body" class="block block-layout-builder block-field-blocknodenews-releasebody"> <div class="field field--name-body field--type-text-with-summary field--label-visually_hidden"> <div class="field__label visually-hidden">Body</div> <div class="field__item"><h3><em lang="EN-US" xml:lang="EN-US" xml:lang="EN-US"><span class="BCX2 NormalTextRun SCXW17887494">Comprehensive systematic review of 25 studies over 25 years reveals consistent evidence of associations between insecticide exposure and lower sperm concentration</span></em><span class="BCX2 EOP SCXW17887494"> </span></h3> <p class="Paragraph SCXW17887494 BCX2"><span class="BCX2 SCXW17887494 TextRun" lang="EN-US" xml:lang="EN-US" xml:lang="EN-US"><span class="BCX2 NormalTextRun SCXW17887494">In a new </span></span><a class="Hyperlink SCXW17887494 BCX2" href="http://www.ehp.niehs.nih.gov/EHP12678" target="_blank"><span class="BCX2 SCXW17887494 TextRun Underlined" lang="EN-US" xml:lang="EN-US" xml:lang="EN-US"><span class="BCX2 NormalTextRun SCXW17887494">systematic review</span></span></a><span class="BCX2 SCXW17887494 TextRun" lang="EN-US" xml:lang="EN-US" xml:lang="EN-US"><span class="BCX2 NormalTextRun SCXW17887494">, </span><span class="BCX2 NormalTextRun SCXW17887494">Melissa J. Perry, Sc.D., MHS, dean of the AV College of Public Health, and Lauren Ellis, MPH, doctoral student at Northeastern University, found</span><span class="BCX2 NormalTextRun SCXW17887494"> </span><span class="BCX2 NormalTextRun SCXW17887494">that there is a strong association between insecticide exposure and lower sperm concentration in adult men globally.</span></span><span class="BCX2 EOP SCXW17887494"> </span></p> <div class="align-left"> <div class="field field--name-image field--type-image field--label-hidden field__item"> <img src="/sites/g/files/yyqcgq291/files/styles/small_content_image/public/2023-11/dean_perry_2023.jpeg?itok=pmWVEX_u" width="233" height="350" alt="Dean Perry smiling arms crossed" loading="lazy" typeof="foaf:Image" /></div> </div> <p class="Paragraph SCXW17887494 BCX2"><span class="BCX2 SCXW17887494 TextRun" lang="EN-US" xml:lang="EN-US" xml:lang="EN-US"><span class="BCX2 NormalTextRun SCXW17887494">“Understanding how insecticides affect sperm concentration in humans is critical given their ubiquity in the environment and documented reproductive hazards. Insecticides are a concern for public health and all men, who are exposed primarily through the consumption of contaminated food and water,” says Ellis.</span></span><span class="BCX2 EOP SCXW17887494"> </span></p> <p class="Paragraph SCXW17887494 BCX2"><span class="BCX2 SCXW17887494 TextRun" lang="EN-US" xml:lang="EN-US" xml:lang="EN-US"><span class="BCX2 NormalTextRun SCXW17887494">The team reviewed decades of human evidence </span><span class="BCX2 NormalTextRun SCXW17887494">regarding</span><span class="BCX2 NormalTextRun SCXW17887494"> the health impacts of exposure to two widely used insecticide classes, </span><span class="BCX2 NormalTextRun SCXW17887494">organophosphates</span><span class="BCX2 NormalTextRun SCXW17887494"> and </span></span><em lang="EN-US" xml:lang="EN-US" xml:lang="EN-US"><span class="BCX2 NormalTextRun SCXW17887494">N</span></em><span class="BCX2 SCXW17887494 TextRun" lang="EN-US" xml:lang="EN-US" xml:lang="EN-US"><span class="BCX2 NormalTextRun SCXW17887494">-methyl carbamates, and found consistent associations with lower sperm concentration, which </span><span class="BCX2 NormalTextRun SCXW17887494">warrants</span><span class="BCX2 NormalTextRun SCXW17887494"> concern, particularly </span><span class="AdvancedProofingIssueV2Themed BCX2 NormalTextRun SCXW17887494">in light of</span><span class="BCX2 NormalTextRun SCXW17887494"> </span><span class="BCX2 NormalTextRun SCXW17887494">observed</span><span class="BCX2 NormalTextRun SCXW17887494"> downward trends in semen quality </span><span class="BCX2 NormalTextRun SCXW17887494">demonstrated</span><span class="BCX2 NormalTextRun SCXW17887494"> by other studies.</span></span><span class="BCX2 EOP SCXW17887494"> </span></p> <p class="Paragraph SCXW17887494 BCX2"><span class="BCX2 SCXW17887494 TextRun" lang="EN-US" xml:lang="EN-US" xml:lang="EN-US"><span class="BCX2 NormalTextRun SCXW17887494">“This review is the most comprehensive evidence sizing up more than 25 years of research on male fertility and reproductive health.</span><span class="BCX2 NormalTextRun SCXW17887494"> The evidence available has reached a point that we must take regulatory action to reduce insecticide exposure,” says Dr. Perry, the senior author on the paper.</span></span><span class="BCX2 EOP SCXW17887494"> </span></p> <p class="Paragraph SCXW17887494 BCX2"><span class="BCX2 SCXW17887494 TextRun" lang="EN-US" xml:lang="EN-US" xml:lang="EN-US"><span class="BCX2 NormalTextRun SCXW17887494">The research team systematically reviewed 25 human studies of occupational and environmental insecticide exposure conducted over the course of</span><span class="BCX2 NormalTextRun SCXW17887494"> </span><span class="BCX2 NormalTextRun SCXW17887494">25 years.</span><span class="BCX2 NormalTextRun SCXW17887494"> </span></span><span class="BCX2 SCXW17887494 TextRun" lang="EN-US" xml:lang="EN-US" xml:lang="EN-US"><span class="BCX2 NormalTextRun SCXW17887494">To the reviewers’ knowledge, this is the most comprehensive systematic review on this topic to date, and the first to use these methods to quantitatively synthesize decades of epidemiological literature.</span></span><span class="BCX2 EOP SCXW17887494"> </span></p> <p class="Paragraph SCXW17887494 BCX2"><span class="BCX2 SCXW17887494 TextRun" lang="EN-US" xml:lang="EN-US" xml:lang="EN-US"><span class="BCX2 NormalTextRun SCXW17887494">“</span></span><a class="Hyperlink SCXW17887494 BCX2" href="http://www.ehp.niehs.nih.gov/EHP12678" target="_blank"><span class="BCX2 SCXW17887494 TextRun Underlined" lang="EN-US" xml:lang="EN-US" xml:lang="EN-US"><span class="BCX2 NormalTextRun SCXW17887494">Adult Organophosphate and Carbamate Insecticide Exposure and Sperm Concentration: A Systematic Review and Meta-Analysis of the Epidemiological Evidence</span></span></a><span class="BCX2 SCXW17887494 TextRun" lang="EN-US" xml:lang="EN-US" xml:lang="EN-US"><span class="BCX2 NormalTextRun SCXW17887494">” was published online in </span></span><em lang="EN-US" xml:lang="EN-US" xml:lang="EN-US"><span class="BCX2 NormalTextRun SCXW17887494">Environmental Health Perspectives in November 2023</span><span class="BCX2 NormalTextRun SCXW17887494"> (</span></em><span class="BCX2 SCXW17887494 TextRun" lang="EN-US" xml:lang="EN-US" xml:lang="EN-US"><span class="BCX2 NormalTextRun SCXW17887494">DOI is 10.1289/EHP12678)</span></span><em lang="EN-US" xml:lang="EN-US" xml:lang="EN-US"><span class="BCX2 NormalTextRun SCXW17887494">.</span><span class="BCX2 NormalTextRun SCXW17887494"> </span></em><span class="BCX2 SCXW17887494 TextRun" lang="EN-US" xml:lang="EN-US" xml:lang="EN-US"><span class="BCX2 NormalTextRun SCXW17887494">Karen Molina, </span><span class="BCX2 NormalTextRun SCXW17887494">C. Rebecca Robbins, and </span><span class="BCX2 NormalTextRun SCXW17887494">Marlaina </span><span class="BCX2 NormalTextRun SCXW17887494 SpellingErrorV2Themed">Freisthler</span><span class="BCX2 NormalTextRun SCXW17887494"> from George Washington University; Daria </span><span class="BCX2 NormalTextRun SCXW17887494 SpellingErrorV2Themed">Sgargi</span><span class="BCX2 NormalTextRun SCXW17887494"> from the Cesare </span><span class="BCX2 NormalTextRun SCXW17887494 SpellingErrorV2Themed">Maltoni</span><span class="BCX2 NormalTextRun SCXW17887494"> Cancer Research Center, </span><span class="BCX2 NormalTextRun SCXW17887494 SpellingErrorV2Themed">Ramazzini</span><span class="BCX2 NormalTextRun SCXW17887494"> Institute; and </span><span class="BCX2 NormalTextRun SCXW17887494">Daniele </span><span class="BCX2 NormalTextRun SCXW17887494 SpellingErrorV2Themed">Mandrioli</span><span class="BCX2 NormalTextRun SCXW17887494"> from the University of Bologna are </span><span class="BCX2 NormalTextRun SCXW17887494">additional</span><span class="BCX2 NormalTextRun SCXW17887494"> authors on the paper.</span></span><span class="BCX2 EOP SCXW17887494"> </span></p> <p class="Paragraph SCXW17887494 BCX2"><span class="BCX2 SCXW17887494 TextRun" lang="EN-US" xml:lang="EN-US" xml:lang="EN-US"><span class="BCX2 NormalTextRun SCXW17887494">Most of the res</span><span class="BCX2 NormalTextRun SCXW17887494">earch was conducted while Perry and Ellis were at George Washington University. There was no outside funding for </span><span class="BCX2 NormalTextRun SCXW17887494">th</span><span class="BCX2 NormalTextRun SCXW17887494">is research.</span></span><span class="BCX2 EOP SCXW17887494"> </span></p> <p class="Paragraph SCXW17887494 BCX2"><span class="BCX2 EOP SCXW17887494"> </span></p> </div> </div> </div> <div data-block-plugin-id="field_block:node:news_release:field_content_topics" class="block block-layout-builder block-field-blocknodenews-releasefield-content-topics"> <h2>Topics</h2> <div class="field field--name-field-content-topics field--type-entity-reference field--label-visually_hidden"> <div class="field__label visually-hidden">Topics</div> <div class="field__items"> <div class="field__item"><a href="/taxonomy/term/7701" hreflang="en">Environmental influences on human fecundity and fertility</a></div> <div class="field__item"><a href="/taxonomy/term/7716" hreflang="en">Fertility</a></div> <div class="field__item"><a href="/taxonomy/term/10951" hreflang="en">Reproductive Epidemiology</a></div> <div class="field__item"><a href="/taxonomy/term/271" hreflang="en">Research</a></div> </div> </div> </div> </div> </div> Tue, 14 Nov 2023 22:30:37 +0000 mthomp7 109976 at